Short Courses and Special Courses

SC39 - Bone Marrow Manifestations of Systemic Disease

Wednesday, March 21, 2018 - 1:30 pm - 5:30 pm
This Short Course session includes up to one-hour break time.

Session Credits:

3 CME and 3 SAMs


Dita Gratzinger, MD, PhD, Stanford Medicine, Stanford, CA
David Czuchlewski, MD, University of New Mexico, Albuquerque, NM 
C. Tracy George, MD, University of New Mexico, Albuquerque, NM 

Course Description

Pathologists evaluating bone marrow biopsies generally focus on identification of hematolymphoid malignancy, with much less awareness of the bone marrow manifestations of systemic disease. Findings of systemic disease in the bone marrow can mimic malignancy, potentially resulting in misdiagnosis; conversely, recognition of systemic disease in the bone marrow can guide clinical management, making recognition of these findings critical for diagnostic pathologists. This case-based course will stress recognition of non-neoplastic systemic disorders manifesting in the bone marrow, including heritable bone marrow failure, storage and immunodeficiency disorders; infection-related marrow abnormalities; drug/toxin-related abnormalities; nutritional, metabolic and endocrine disorders; and rheumatologic/autoimmune disorders. The course is designed for advanced residents, fellows, surgical pathologists and hematopathologists.

Learning Objectives

Upon completion of this educational activity, the learner will be able to:

  • Provide a comprehensive differential diagnosis for systemic causes of abnormalities of hematopoiesis and of non-hematopoietic marrow
  • Identify clinical and laboratory information needed to support non-neoplastic diagnoses in the marrow
  • Recognize the morphologic findings associated with specific systemic disorders as manifested in the routine diagnostic bone marrow biopsy.


Continuing Medical Education and Maintenance of Certification

The United States and Canadian Academy of Pathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this live activity for a maximum of 3 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The USCAP is approved by the American Board of Pathology (ABP) to offer Self-Assessment credits (SAMs) for the purpose of meeting the ABP requirements for Maintenance of Certification (MOC). Physicians must take and pass the post-test in order to claim SAMs credit.

Physicians can earn a maximum of 3 SAM credit hours.


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