Short Courses and Special Courses

SC40 – Hematolymphoid Lesions at the Borderline Between Benign and Malignant: Finding Your Way Out of Uncertainty

Wednesday, March 21, 2018 - 8:00 am - 12:00 pm
This Short Course session includes up to a one-hour break.

Session Credits:

3 CME and 3 SAMs


Eric D. Hsi, MD, Cleveland Clinic, Cleveland, OH
Carlos E. Bueso-Ramos, MD, PhD, University of Texas MD Anderson Cancer Center, Houston, TX
Megan O. Nakashima, MD, Cleveland Clinic, Cleveland, OH

Course Description

There are several hematolymphoid lesions which are at the interface between processes which are clearly malignant and others which are clinically benign, including in situ lymphomas, EBV-associated lymphoproliferative disorders, and idiopathic cytopenias of undetermined significance. As more data is accumulated our understanding of these entities is constantly evolving. Despite increases in knowledge, these borderline lesions remain difficult to diagnose. This course will be based on case examples which will be available for review as digital slides and static images prior to the meeting. It is designed for pathologists in training, and practicing hematopathologists and surgical pathologists. After the course, registrants will be given access to PowerPoint slides used during the presentation. Topics to be discussed include in situ lymphomas, cutaneous pseudolymphomas, clonal T-cell populations detected during immune-altered states, monoclonal gammopathy of undetermined significance, non-post-transplant EBV-associated lymphoproliferative disorders, chronic eosinophilia, and idiopathic cytopenia of undermined significance, as well as other related lesions. Emphasis will be placed on morphologic features and differential diagnosis of these entities, as well as guidance regarding appropriate ancillary testing. A brief review of current understanding of pathogenesis and prognosis will also be discussed for each lesion.

Learning Objectives

Upon completion of this educational activity, the learner will be able to:

  • Recognize and diagnose these challenging lesions and differentiate them from potential diagnostic pitfalls
  • Know what ancillary testing is appropriate in the diagnostic workup of these lesions, and through an updated understanding of the biology of these processes
  • Construct meaningful diagnostic report for their clinical colleagues


Continuing Medical Education and Maintenance of Certification

The United States and Canadian Academy of Pathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this live activity for a maximum of 3 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The USCAP is approved by the American Board of Pathology (ABP) to offer Self-Assessment credits (SAMs) for the purpose of meeting the ABP requirements for Maintenance of Certification (MOC). Physicians must take and pass the post-test in order to claim SAMs credit.

Physicians can earn a maximum of 3 SAM credit hours.


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