Short Courses and Special Courses

SC47 - Solutions to Old and Emerging Challenges in Uterine Pathology: Morphology, Molecular or Both

Wednesday, March 21, 2018 - 8:00 am - 12:00 pm
This Short Course session includes up to a one-hour break.

Session Credits:

3 CME and 3 SAMs


Bojana Djordjevic, MD, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Carlos Parra-Herran, MD, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Russell Broaddus, MD, PhD, MD Anderson Cancer Center, The University of Texas, Houston, TX
Karuna Garg, MD, University of California San Francisco, San Francisco, CA

Course Description

Our understanding of the biology of uterine tumors continues to grow and fuel an evolution in diagnostic and therapeutic approaches. This course is designed for general pathologists and pathologists in training who are looking to become more familiar with how new discoveries in uterine pathology should translate into their clinical practice. When is the use of ancillary techniques, such as immunohistochemistry and molecular testing, necessary to make the correct diagnosis or yield prognostically significant information? When is morphologic evaluation alone an acceptable standard of practice? This constitutes the fundamental practice gap to be addressed in this short course. The following entities will be discussed in this context: endometrial carcinoma, progestin treated endometrial hyperplasia and carcinoma, endometrial stromal sarcoma, adenosarcoma, uterine smooth muscle neoplasms and uterine perivascular epithelioid tumors. Hereditary syndromes involve both the epithelial and mesenchymal compartments of the uterus. To help in accurately identifying these syndromes, this course will also outline systematic tumor screening approaches within the pathology laboratory, algorithmic and cost-effective utilization of ancillary testing, interpretation of equivocal results and reporting recommendations.

Learning Objectives

Upon completion of this educational activity, the learner will be able to:

  • Identify scenarios in the practice of gynecologic pathology in which the use of molecular testing and immunohistochemistry is key for diagnosis and management of uterine glandular and mesenchymal lesions
  • Apply strict histopathologic criteria when approaching entities where morphological interpretation remains the cornerstone of diagnosis
  • Interpret typical and unusual mismatch immunohistochemistry repair patterns and know when to order additional molecular testing


Continuing Medical Education and Maintenance of Certification

The United States and Canadian Academy of Pathology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The United States and Canadian Academy of Pathology designates this live activity for a maximum of 3 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The USCAP is approved by the American Board of Pathology (ABP) to offer Self-Assessment credits (SAMs) for the purpose of meeting the ABP requirements for Maintenance of Certification (MOC). Physicians must take and pass the post-test in order to claim SAMs credit.

Physicians can earn a maximum of 3 SAM credit hours.


Return to 2018 Annual Meeting Short Course Page


view more